Monday, March 16, 2015
Buerger’s disease
also known as Thrombangitis obliterans
Common medium vessel occlusive vasculitis of peripheral limbs seen exclusively in male smokers, and a common cause for limb amputation.
Common in indian subcontinent.
Associations with certain HLA types and with antiendothelial antibodies have been found.
Tibial most commonly affected artery
Microscopic : shows acute or chronic inflammatory infiltrates according to the duration of disease, thrombus occluding the lumen, recanalisation of thrombus at places, microabscesses and granuloma formation, and fibrosis.
Common medium vessel occlusive vasculitis of peripheral limbs seen exclusively in male smokers, and a common cause for limb amputation.
Common in indian subcontinent.
Associations with certain HLA types and with antiendothelial antibodies have been found.
Tibial most commonly affected artery
Microscopic : shows acute or chronic inflammatory infiltrates according to the duration of disease, thrombus occluding the lumen, recanalisation of thrombus at places, microabscesses and granuloma formation, and fibrosis.
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